BRD-K75999307_NCGC00182357-01_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-K75999307_NCGC00182357-01_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
C6ORF62 chromosome 6 open reading frame 62
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCNG2 cyclin G2
CDC25B cell division cycle 25B
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC4 chloride intracellular channel 4
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
EFS embryonal Fyn-associated substrate
EIF5A eukaryotic translation initiation factor 5A
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FAM46A family with sequence similarity 46, member A
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KIF14 kinesin family member 14
LMO4 LIM domain only 4
LPAR1 lysophosphatidic acid receptor 1
LYPD1 LY6/PLAUR domain containing 1
MARCKS myristoylated alanine-rich protein kinase C substrate
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP7 matrix metallopeptidase 7
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NQO1 NAD(P)H dehydrogenase, quinone 1
PGD phosphogluconate dehydrogenase
PLIN2 perilipin 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRKACB protein kinase, cAMP-dependent, catalytic, beta
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RIT1 Ras-like without CAAX 1
S100P S100 calcium binding protein P
SCGB2A2 secretoglobin, family 2A, member 2
SDCBP syndecan binding protein (syntenin)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
TALDO1 transaldolase 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNPO1 transportin 1
TSPAN13 tetraspanin 13
TUBB2B tubulin, beta 2B class IIb
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ACPP acid phosphatase, prostate
B3GNT1
C1ORF116 chromosome 1 open reading frame 116
CHERP calcium homeostasis endoplasmic reticulum protein
COG7 component of oligomeric golgi complex 7
CPA3 carboxypeptidase A3 (mast cell)
CRYM crystallin, mu
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
GRWD1 glutamate-rich WD repeat containing 1
HOXA10 homeobox A10
ICMT isoprenylcysteine carboxyl methyltransferase
IFITM3 interferon induced transmembrane protein 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MCM2 minichromosome maintenance complex component 2
MCM4 minichromosome maintenance complex component 4
NEFH neurofilament, heavy polypeptide
NFE2L3 nuclear factor, erythroid 2-like 3
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PRNP prion protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
SPON1 spondin 1, extracellular matrix protein
ST7 suppression of tumorigenicity 7
TSPAN4 tetraspanin 4
WFDC1 WAP four-disulfide core domain 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta