BRD-K75430629_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K75430629_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT9 acyl-CoA thioesterase 9
ALCAM activated leukocyte cell adhesion molecule
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
CRIP1 cysteine-rich protein 1 (intestinal)
CST3 cystatin C
DST dystonin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
F5 coagulation factor V (proaccelerin, labile factor)
GPX7 glutathione peroxidase 7
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
MSX1 msh homeobox 1
PTX3 pentraxin 3, long
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRSF6 serine/arginine-rich splicing factor 6
TMX4 thioredoxin-related transmembrane protein 4

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
C3 complement component 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC2B C-type lectin domain family 2, member B
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
CRABP1 cellular retinoic acid binding protein 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPAS1 endothelial PAS domain protein 1
HOPX HOP homeobox
LIMCH1 LIM and calponin homology domains 1
MMP2 matrix metallopeptidase 2
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCAM1 neural cell adhesion molecule 1
PAPD7 PAP associated domain containing 7
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPOX protoporphyrinogen oxidase
PTRF polymerase I and transcript release factor
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SELENBP1 selenium binding protein 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHB Src homology 2 domain containing adaptor protein B
SNAI2 snail family zinc finger 2
SNX7 sorting nexin 7
SOX11 SRY (sex determining region Y)-box 11
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STC1 stanniocalcin 1
SULF1 sulfatase 1
TFPI2 tissue factor pathway inhibitor 2
THBS2 thrombospondin 2
TRPS1 trichorhinophalangeal syndrome I
XIST X inactive specific transcript (non-protein coding)
ZNF395 zinc finger protein 395