BRD-K74840245_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K74840245_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAX BCL2-associated X protein
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
COL4A5 collagen, type IV, alpha 5
COLEC12 collectin sub-family member 12
CST3 cystatin C
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LTF lactotransferrin
MAP7 microtubule-associated protein 7
NELL2 NEL-like 2 (chicken)
PDLIM3 PDZ and LIM domain 3
PON3 paraoxonase 3
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)

decreased expression

Symbol Name
CAV2 caveolin 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CRYZ crystallin, zeta (quinone reductase)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLD dihydrolipoamide dehydrogenase
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
G0S2 G0/G1 switch 2
LYPLA1 lysophospholipase I
MARCKS myristoylated alanine-rich protein kinase C substrate
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NFIB nuclear factor I/B
PLS1 plastin 1
PRPF4 pre-mRNA processing factor 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFN stratifin
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SMS spermine synthase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TOP2A topoisomerase (DNA) II alpha 170kDa
UGCG UDP-glucose ceramide glucosyltransferase
XBP1 X-box binding protein 1
XPO7 exportin 7