BRD-K74767048_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K74767048_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ARMCX1 armadillo repeat containing, X-linked 1
BICC1 BicC family RNA binding protein 1
BTG2 BTG family, member 2
CAV1 caveolin 1, caveolae protein, 22kDa
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CFD complement factor D (adipsin)
DHRS2 dehydrogenase/reductase (SDR family) member 2
G0S2 G0/G1 switch 2
MAN1A1 mannosidase, alpha, class 1A, member 1
MDFIC MyoD family inhibitor domain containing
MT1F metallothionein 1F
PDGFD platelet derived growth factor D
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFRP1 secreted frizzled-related protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TMEM45A transmembrane protein 45A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
C1QB complement component 1, q subcomponent, B chain
CLIC4 chloride intracellular channel 4
EBP emopamil binding protein (sterol isomerase)
LAPTM4B lysosomal protein transmembrane 4 beta
MSLN mesothelin
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
TLR4 toll-like receptor 4