BRD-K74486276_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K74486276_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AHNAK AHNAK nucleoprotein
C6ORF62 chromosome 6 open reading frame 62
CD36 CD36 molecule (thrombospondin receptor)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EBP emopamil binding protein (sterol isomerase)
ELOVL5 ELOVL fatty acid elongase 5
ELOVL6 ELOVL fatty acid elongase 6
FABP4 fatty acid binding protein 4, adipocyte
FASN fatty acid synthase
GLIPR1 GLI pathogenesis-related 1
GNG12 guanine nucleotide binding protein (G protein), gamma 12
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LAMB1 laminin, beta 1
METTL7A methyltransferase like 7A
RPS11 ribosomal protein S11
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SRPX sushi-repeat containing protein, X-linked
STEAP1 six transmembrane epithelial antigen of the prostate 1
TMEM97 transmembrane protein 97

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP8 A kinase (PRKA) anchor protein 8
CA2 carbonic anhydrase II
CPA3 carboxypeptidase A3 (mast cell)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GATA2 GATA binding protein 2
GEM GTP binding protein overexpressed in skeletal muscle
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
P3H2 prolyl 3-hydroxylase 2
SNX7 sorting nexin 7
TOR1A torsin family 1, member A (torsin A)