BRD-K74447990_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K74447990_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ALCAM activated leukocyte cell adhesion molecule
ALG8 ALG8, alpha-1,3-glucosyltransferase
BLNK B-cell linker
CCL2 chemokine (C-C motif) ligand 2
CD1E CD1e molecule
CD200 CD200 molecule
CKAP4 cytoskeleton-associated protein 4
CLNS1A chloride channel, nucleotide-sensitive, 1A
CPE carboxypeptidase E
F2RL1 coagulation factor II (thrombin) receptor-like 1
FBP1 fructose-1,6-bisphosphatase 1
FGL2 fibrinogen-like 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
IL6R interleukin 6 receptor
ITM2C integral membrane protein 2C
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KCTD14 potassium channel tetramerization domain containing 14
MFAP5 microfibrillar associated protein 5
MTMR11 myotubularin related protein 11
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NAV2 neuron navigator 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PI3 peptidase inhibitor 3, skin-derived
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
RAP1GAP2 RAP1 GTPase activating protein 2
RBP1 retinol binding protein 1, cellular
RSF1 remodeling and spacing factor 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCG5 secretogranin V
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SULF1 sulfatase 1
TOX3 TOX high mobility group box family member 3
UVRAG UV radiation resistance associated
VSNL1 visinin-like 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
C1QA complement component 1, q subcomponent, A chain
CD24 CD24 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP1 dual specificity phosphatase 1
FBN2 fibrillin 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HN1 hematological and neurological expressed 1
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
KRT19 keratin 19, type I
LHFP lipoma HMGIC fusion partner
LIMCH1 LIM and calponin homology domains 1
LOC100505650 uncharacterized LOC100505650
MGP matrix Gla protein
MYBPC1 myosin binding protein C, slow type
NEB nebulin
NPDC1 neural proliferation, differentiation and control, 1
PCNA proliferating cell nuclear antigen
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKM pyruvate kinase, muscle
RHOBTB3 Rho-related BTB domain containing 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLN sarcolipin
TMEM100 transmembrane protein 100
TSPAN13 tetraspanin 13
TTN titin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)