BRD-K73397362_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K73397362_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA5 annexin A5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BCHE butyrylcholinesterase
C1ORF115 chromosome 1 open reading frame 115
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPZB capping protein (actin filament) muscle Z-line, beta
CFLAR CASP8 and FADD-like apoptosis regulator
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FBP1 fructose-1,6-bisphosphatase 1
G0S2 G0/G1 switch 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LEF1 lymphoid enhancer-binding factor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAP1L1 nucleosome assembly protein 1-like 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP3 nuclear receptor interacting protein 3
OSBPL8 oxysterol binding protein-like 8
SATB1 SATB homeobox 1
SELPLG selectin P ligand
SLC16A6 solute carrier family 16, member 6
TNPO1 transportin 1
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
AHNAK2 AHNAK nucleoprotein 2
CCND2 cyclin D2
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC4 chloride intracellular channel 4
CLU clusterin
CNN3 calponin 3, acidic
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
DPYSL3 dihydropyrimidinase-like 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FBN2 fibrillin 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GSTA1 glutathione S-transferase alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGFBP5 insulin-like growth factor binding protein 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LOC100505650 uncharacterized LOC100505650
LPAR1 lysophosphatidic acid receptor 1
LTBP1 latent transforming growth factor beta binding protein 1
MAP7 microtubule-associated protein 7
MFAP5 microfibrillar associated protein 5
MXRA7 matrix-remodelling associated 7
NEBL nebulette
NTS neurotensin
PAPD7 PAP associated domain containing 7
PDGFD platelet derived growth factor D
PMM2 phosphomannomutase 2
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SGK1 serum/glucocorticoid regulated kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
ZNF395 zinc finger protein 395
ZNF512B zinc finger protein 512B
ZNF586 zinc finger protein 586