BRD-K73395020_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

105 genes differentially expressed following the BRD-K73395020_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
AMIGO2 adhesion molecule with Ig-like domain 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
BHLHE40 basic helix-loop-helix family, member e40
BLVRB biliverdin reductase B
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCNE2 cyclin E2
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLU clusterin
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
FAM162A family with sequence similarity 162, member A
FAM57A family with sequence similarity 57, member A
FECH ferrochelatase
GBE1 glucan (1,4-alpha-), branching enzyme 1
GPI glucose-6-phosphate isomerase
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMOX1 heme oxygenase 1
IGHM immunoglobulin heavy constant mu
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
KDM3A lysine (K)-specific demethylase 3A
MAGEA6 melanoma antigen family A6
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP12 matrix metallopeptidase 12
MT1X metallothionein 1X
MXI1 MAX interactor 1, dimerization protein
NARF nuclear prelamin A recognition factor
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PIR pirin (iron-binding nuclear protein)
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRDX2 peroxiredoxin 2
RNF167 ring finger protein 167
SATB1 SATB homeobox 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3BP4 SH3-domain binding protein 4
SKAP2 src kinase associated phosphoprotein 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORBS1 sorbin and SH3 domain containing 1
SORD sorbitol dehydrogenase
SPAG4 sperm associated antigen 4
STC1 stanniocalcin 1
SYBU syntabulin (syntaxin-interacting)
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TMEM45A transmembrane protein 45A
TMEM47 transmembrane protein 47
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TPGS2 tubulin polyglutamylase complex subunit 2
TSPAN8 tetraspanin 8
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor
XK X-linked Kx blood group

decreased expression

Symbol Name
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AURKA aurora kinase A
C1ORF106 chromosome 1 open reading frame 106
CCNF cyclin F
CDC25B cell division cycle 25B
CDC42 cell division cycle 42
CDCA4 cell division cycle associated 4
CENPF centromere protein F, 350/400kDa
CPB1 carboxypeptidase B1 (tissue)
CRABP2 cellular retinoic acid binding protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EREG epiregulin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NRP1 neuropilin 1
PLK1 polo-like kinase 1
PSRC1 proline/serine-rich coiled-coil 1
RPP38 ribonuclease P/MRP 38kDa subunit
TACC3 transforming, acidic coiled-coil containing protein 3
TFPI2 tissue factor pathway inhibitor 2
TROAP trophinin associated protein
UBE2C ubiquitin-conjugating enzyme E2C
VTCN1 V-set domain containing T cell activation inhibitor 1