BRD-K73395020_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K73395020_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
AXL AXL receptor tyrosine kinase
BAG3 BCL2-associated athanogene 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CCNE2 cyclin E2
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CLC Charcot-Leyden crystal galectin
COL6A3 collagen, type VI, alpha 3
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
FADS1 fatty acid desaturase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
FST follistatin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPRC5A G protein-coupled receptor, class C, group 5, member A
H1F0 H1 histone family, member 0
HK2 hexokinase 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IER2 immediate early response 2
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KRT14 keratin 14, type I
LOXL2 lysyl oxidase-like 2
MSMO1 methylsterol monooxygenase 1
NRG1 neuregulin 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PEA15 phosphoprotein enriched in astrocytes 15
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI3 peptidase inhibitor 3, skin-derived
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPIF peptidylprolyl isomerase F
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMAD3 SMAD family member 3
SQLE squalene epoxidase
TNS3 tensin 3
TPM2 tropomyosin 2 (beta)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ARID5B AT rich interactive domain 5B (MRF1-like)
CCL4 chemokine (C-C motif) ligand 4
CCNF cyclin F
CENPA centromere protein A
CENPE centromere protein E, 312kDa
GATA2 GATA binding protein 2
HMGN3 high mobility group nucleosomal binding domain 3
KIF20A kinesin family member 20A
LAMP1 lysosomal-associated membrane protein 1
LGALS3 lectin, galactoside-binding, soluble, 3
MAOA monoamine oxidase A
NRIP1 nuclear receptor interacting protein 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBM47 RNA binding motif protein 47
SIDT2 SID1 transmembrane family, member 2
SMS spermine synthase