BRD-K73290745_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K73290745_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
ARMCX1 armadillo repeat containing, X-linked 1
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
CCNG2 cyclin G2
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
COL15A1 collagen, type XV, alpha 1
CPE carboxypeptidase E
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
FDPS farnesyl diphosphate synthase
FST follistatin
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
HIST1H2BD histone cluster 1, H2bd
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBP7 insulin-like growth factor binding protein 7
INHBB inhibin, beta B
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
KRT23 keratin 23, type I
LDLR low density lipoprotein receptor
LTB lymphotoxin beta (TNF superfamily, member 3)
MMP7 matrix metallopeptidase 7
MSMO1 methylsterol monooxygenase 1
MVP major vault protein
NSDHL NAD(P) dependent steroid dehydrogenase-like
PYCARD PYD and CARD domain containing
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
THBS2 thrombospondin 2
TM7SF2 transmembrane 7 superfamily member 2
TPM2 tropomyosin 2 (beta)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
COL2A1 collagen, type II, alpha 1
ELANE elastase, neutrophil expressed
KIAA0368 KIAA0368
MRPS2 mitochondrial ribosomal protein S2
PMP22 peripheral myelin protein 22
TRH thyrotropin-releasing hormone