BRD-K73290745_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K73290745_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
CST1 cystatin SN
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
FDPS farnesyl diphosphate synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
IPO13 importin 13
LDLR low density lipoprotein receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP7 microtubule-associated protein 7
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

decreased expression

Symbol Name
CD24 CD24 molecule
GCH1 GTP cyclohydrolase 1
HBEGF heparin-binding EGF-like growth factor
LYZ lysozyme
MMP9 matrix metallopeptidase 9
NSF N-ethylmaleimide-sensitive factor
ODC1 ornithine decarboxylase 1
RGS2 regulator of G-protein signaling 2