BRD-K73155123_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K73155123_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
ARHGAP29 Rho GTPase activating protein 29
ARMCX1 armadillo repeat containing, X-linked 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CA2 carbonic anhydrase II
CD200 CD200 molecule
CD24 CD24 molecule
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
DDIT4 DNA-damage-inducible transcript 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DOK5 docking protein 5
EPAS1 endothelial PAS domain protein 1
FAM69A family with sequence similarity 69, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FRZB frizzled-related protein
GNG11 guanine nucleotide binding protein (G protein), gamma 11
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HIST1H4J histone cluster 1, H4j
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JAG1 jagged 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLK5 kallikrein-related peptidase 5
KRT19 keratin 19, type I
LPAR6 lysophosphatidic acid receptor 6
MAP7 microtubule-associated protein 7
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MSMB microseminoprotein, beta-
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTSS1 metastasis suppressor 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPTX2 neuronal pentraxin II
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PTPRO protein tyrosine phosphatase, receptor type, O
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SAT1 spermidine/spermine N1-acetyltransferase 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ANXA5 annexin A5
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK6 cyclin-dependent kinase 6
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFLAR CASP8 and FADD-like apoptosis regulator
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FBLN1 fibulin 1
FLNA filamin A, alpha
FPGS folylpolyglutamate synthase
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GMDS GDP-mannose 4,6-dehydratase
GOLM1 golgi membrane protein 1
GPC3 glypican 3
H1F0 H1 histone family, member 0
HOXC6 homeobox C6
IL6ST interleukin 6 signal transducer
LEF1 lymphoid enhancer-binding factor 1
LTBP3 latent transforming growth factor beta binding protein 3
MAN2B1 mannosidase, alpha, class 2B, member 1
MATN2 matrilin 2
MSRB2 methionine sulfoxide reductase B2
PCM1 pericentriolar material 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPIF peptidylprolyl isomerase F
RAD23B RAD23 homolog B (S. cerevisiae)
STXBP1 syntaxin binding protein 1
STXBP2 syntaxin binding protein 2
TMEM164 transmembrane protein 164
TNC tenascin C
UBE2E1 ubiquitin-conjugating enzyme E2E 1
ZYX zyxin