BRD-K73109821_-666_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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84 genes differentially expressed following the BRD-K73109821_-666_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
AREG amphiregulin
ATP11B ATPase, class VI, type 11B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CTAG2 cancer/testis antigen 2
GAGE3 G antigen 3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
HGD homogentisate 1,2-dioxygenase
HOPX HOP homeobox
HOXD1 homeobox D1
IGL immunoglobulin lambda locus
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
KRT81 keratin 81, type II
LDHB lactate dehydrogenase B
LY75 lymphocyte antigen 75
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MPZL2 myelin protein zero-like 2
NLRP2 NLR family, pyrin domain containing 2
NRGN neurogranin (protein kinase C substrate, RC3)
OAT ornithine aminotransferase
PON3 paraoxonase 3
POSTN periostin, osteoblast specific factor
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SELENBP1 selenium binding protein 1
TBX3 T-box 3
TBXA2R thromboxane A2 receptor
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACTC1 actin, alpha, cardiac muscle 1
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C3 aldo-keto reductase family 1, member C3
ANXA6 annexin A6
AOX1 aldehyde oxidase 1
BASP1 brain abundant, membrane attached signal protein 1
CCND1 cyclin D1
CTBP1 C-terminal binding protein 1
DES desmin
EDF1 endothelial differentiation-related factor 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EMX2 empty spiracles homeobox 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GAA glucosidase, alpha; acid
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IRS1 insulin receptor substrate 1
KLF4 Kruppel-like factor 4 (gut)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOXL1 lysyl oxidase-like 1
METRN meteorin, glial cell differentiation regulator
MRPL12 mitochondrial ribosomal protein L12
MTA1 metastasis associated 1
MYL9 myosin, light chain 9, regulatory
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRCAM neuronal cell adhesion molecule
PEBP1 phosphatidylethanolamine binding protein 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POPDC3 popeye domain containing 3
PRMT1 protein arginine methyltransferase 1
PROM1 prominin 1
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAD23B RAD23 homolog B (S. cerevisiae)
RHOB ras homolog family member B
SET SET nuclear proto-oncogene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SPATS2L spermatogenesis associated, serine-rich 2-like
SRPX sushi-repeat containing protein, X-linked
TFF1 trefoil factor 1
TP53 tumor protein p53
TPM2 tropomyosin 2 (beta)
TWF2 twinfilin actin binding protein 2
VAT1 vesicle amine transport 1
ZIC1 Zic family member 1