BRD-K72895815_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K72895815_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX5 arachidonate 5-lipoxygenase
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CCL5 chemokine (C-C motif) ligand 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CTSZ cathepsin Z
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
EFHD2 EF-hand domain family, member D2
EPHA2 EPH receptor A2
ERGIC2 ERGIC and golgi 2
FGG fibrinogen gamma chain
FOSL1 FOS-like antigen 1
GNLY granulysin
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
LCN2 lipocalin 2
LTF lactotransferrin
MKNK1 MAP kinase interacting serine/threonine kinase 1
NAMPT nicotinamide phosphoribosyltransferase
PHLDA2 pleckstrin homology-like domain, family A, member 2
RAD23B RAD23 homolog B (S. cerevisiae)
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RND3 Rho family GTPase 3
S100A12 S100 calcium binding protein A12
SLC12A8 solute carrier family 12, member 8
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLPI secretory leukocyte peptidase inhibitor
SRGN serglycin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
AURKB aurora kinase B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCNG2 cyclin G2
CHRDL1 chordin-like 1
CLIC4 chloride intracellular channel 4
CST3 cystatin C
CYFIP2 cytoplasmic FMR1 interacting protein 2
DLC1 DLC1 Rho GTPase activating protein
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FABP1 fatty acid binding protein 1, liver
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FLNA filamin A, alpha
GHR growth hormone receptor
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HIST1H2BG histone cluster 1, H2bg
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
ITM2A integral membrane protein 2A
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
MAP7 microtubule-associated protein 7
MGP matrix Gla protein
MUC1 mucin 1, cell surface associated
MYB v-myb avian myeloblastosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
NAV2 neuron navigator 2
PAH phenylalanine hydroxylase
PBX1 pre-B-cell leukemia homeobox 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SCAND1 SCAN domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPEN spen family transcriptional repressor
STK26 serine/threonine protein kinase 26
TBC1D16 TBC1 domain family, member 16
TMSB15A thymosin beta 15a
TOX3 TOX high mobility group box family member 3
TRAK2 trafficking protein, kinesin binding 2
TUBA1A tubulin, alpha 1a