BRD-K72895815_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

86 genes differentially expressed following the BRD-K72895815_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
ANGPTL2 angiopoietin-like 2
ANK2 ankyrin 2, neuronal
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BLVRB biliverdin reductase B
BPHL biphenyl hydrolase-like (serine hydrolase)
C10ORF10 chromosome 10 open reading frame 10
CD163 CD163 molecule
CD99 CD99 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLGN calmegin
COL1A1 collagen, type I, alpha 1
CTSK cathepsin K
CTSL cathepsin L
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
GDF15 growth differentiation factor 15
GPNMB glycoprotein (transmembrane) nmb
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP6 insulin-like growth factor binding protein 6
JCHAIN joining chain of multimeric IgA and IgM
LY96 lymphocyte antigen 96
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1A1 mannosidase, alpha, class 1A, member 1
MME membrane metallo-endopeptidase
MPO myeloperoxidase
MXRA5 matrix-remodelling associated 5
NRCAM neuronal cell adhesion molecule
NUPR1 nuclear protein, transcriptional regulator, 1
PDGFRL platelet-derived growth factor receptor-like
PSAP prosaposin
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFRP4 secreted frizzled-related protein 4
SMAD1 SMAD family member 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SQSTM1 sequestosome 1
SULF1 sulfatase 1
TXNRD1 thioredoxin reductase 1
VTCN1 V-set domain containing T cell activation inhibitor 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
AREG amphiregulin
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
BMI1 BMI1 proto-oncogene, polycomb ring finger
BST2 bone marrow stromal cell antigen 2
CCND1 cyclin D1
CD59 CD59 molecule, complement regulatory protein
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
EFNB2 ephrin-B2
ERBB3 erb-b2 receptor tyrosine kinase 3
EREG epiregulin
IER3 immediate early response 3
MAGT1 magnesium transporter 1
MSH6 mutS homolog 6
PLK1 polo-like kinase 1
SCARB2 scavenger receptor class B, member 2
SDC2 syndecan 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TGOLN2 trans-golgi network protein 2
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TKTL1 transketolase-like 1
TMEM2 transmembrane protein 2
UBE2S ubiquitin-conjugating enzyme E2S