BRD-K72864428_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K72864428_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA1 actin, alpha 1, skeletal muscle
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AURKB aurora kinase B
CD93 CD93 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
CX3CR1 chemokine (C-X3-C motif) receptor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FMO2 flavin containing monooxygenase 2 (non-functional)
HHEX hematopoietically expressed homeobox
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT19 keratin 19, type I
MB myoglobin
MYBPC2 myosin binding protein C, fast type
MYH2 myosin, heavy chain 2, skeletal muscle, adult
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYOF myoferlin
NEB nebulin
NRP1 neuropilin 1
PLK2 polo-like kinase 2
RGS5 regulator of G-protein signaling 5
SCGB2A1 secretoglobin, family 2A, member 1
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TTN titin
UBE3B ubiquitin protein ligase E3B
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
CHPT1 choline phosphotransferase 1
CXADR coxsackie virus and adenovirus receptor
LIMS1 LIM and senescent cell antigen-like domains 1
LUC7L3 LUC7-like 3 (S. cerevisiae)
MEGF9 multiple EGF-like-domains 9
METTL7A methyltransferase like 7A
MTDH metadherin
PTPRC protein tyrosine phosphatase, receptor type, C
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
UGDH UDP-glucose 6-dehydrogenase
XPO7 exportin 7