BRD-K72732164_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K72732164_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZU1 azurocidin 1
CD36 CD36 molecule (thrombospondin receptor)
CFD complement factor D (adipsin)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COMP cartilage oligomeric matrix protein
CSTA cystatin A (stefin A)
DACT1 dishevelled-binding antagonist of beta-catenin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
FGFR3 fibroblast growth factor receptor 3
FLRT2 fibronectin leucine rich transmembrane protein 2
FST follistatin
GJA1 gap junction protein, alpha 1, 43kDa
GREM1 gremlin 1, DAN family BMP antagonist
MPO myeloperoxidase
NPIPB3 nuclear pore complex interacting protein family, member B3
PPOX protoporphyrinogen oxidase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGCC regulator of cell cycle
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFRP4 secreted frizzled-related protein 4
THY1 Thy-1 cell surface antigen
TNNT1 troponin T type 1 (skeletal, slow)
TNS3 tensin 3
TRIM22 tripartite motif containing 22

decreased expression

Symbol Name
DKK1 dickkopf WNT signaling pathway inhibitor 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MET MET proto-oncogene, receptor tyrosine kinase
OLFM4 olfactomedin 4
PLAC8 placenta-specific 8
PLK2 polo-like kinase 2
PRKCA protein kinase C, alpha
PROM1 prominin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TFF1 trefoil factor 1
TM4SF1 transmembrane 4 L six family member 1