BRD-K72726508_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K72726508_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CIB1 calcium and integrin binding 1 (calmyrin)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DSE dermatan sulfate epimerase
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
PGD phosphogluconate dehydrogenase
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PPARG peroxisome proliferator-activated receptor gamma
PYGL phosphorylase, glycogen, liver
RAP1GAP RAP1 GTPase activating protein
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SMAD3 SMAD family member 3
TGFBI transforming growth factor, beta-induced, 68kDa
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
CA2 carbonic anhydrase II
CCND2 cyclin D2
DLK1 delta-like 1 homolog (Drosophila)
FGFR3 fibroblast growth factor receptor 3
ITGA6 integrin, alpha 6
MUC1 mucin 1, cell surface associated
PEG3 paternally expressed 3
PRSS23 protease, serine, 23
PTGER4 prostaglandin E receptor 4 (subtype EP4)
REEP1 receptor accessory protein 1
SCGB2A1 secretoglobin, family 2A, member 1
TOX3 TOX high mobility group box family member 3
ZWINT ZW10 interacting kinetochore protein