BRD-K72703948_ZM-447439_A375_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-K72703948_ZM-447439_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRA3 adhesion G protein-coupled receptor A3
ALDOA aldolase A, fructose-bisphosphate
AREG amphiregulin
ATF3 activating transcription factor 3
AVPI1 arginine vasopressin-induced 1
BEX4 brain expressed, X-linked 4
BIK BCL2-interacting killer (apoptosis-inducing)
BTG2 BTG family, member 2
CCNG2 cyclin G2
CD9 CD9 molecule
CD96 CD96 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCL13 chemokine (C-X-C motif) ligand 13
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDB2 damage-specific DNA binding protein 2, 48kDa
DGKA diacylglycerol kinase, alpha 80kDa
DUSP14 dual specificity phosphatase 14
FDXR ferredoxin reductase
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GDF15 growth differentiation factor 15
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HOXB2 homeobox B2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KRT18 keratin 18, type I
LYPD1 LY6/PLAUR domain containing 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MICALL1 MICAL-like 1
NNMT nicotinamide N-methyltransferase
NPY neuropeptide Y
PDLIM1 PDZ and LIM domain 1
PRRC2C proline-rich coiled-coil 2C
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RPS27L ribosomal protein S27-like
S100A10 S100 calcium binding protein A10
SESN1 sestrin 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STAB1 stabilin 1
STC2 stanniocalcin 2
SYNM synemin, intermediate filament protein
TARP TCR gamma alternate reading frame protein
TIGAR TP53 induced glycolysis regulatory phosphatase
VAMP8 vesicle-associated membrane protein 8
VDAC1 voltage-dependent anion channel 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BSG basigin (Ok blood group)
C3 complement component 3
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
DPYD dihydropyrimidine dehydrogenase
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
F3 coagulation factor III (thromboplastin, tissue factor)
FGL2 fibrinogen-like 2
FSTL1 follistatin-like 1
GCH1 GTP cyclohydrolase 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HIST1H2BG histone cluster 1, H2bg
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LIPG lipase, endothelial
LOXL1 lysyl oxidase-like 1
LTF lactotransferrin
MCM6 minichromosome maintenance complex component 6
MFAP5 microfibrillar associated protein 5
MGP matrix Gla protein
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MUC4 mucin 4, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
PLAC8 placenta-specific 8
PLN phospholamban
PLXNC1 plexin C1
PODXL podocalyxin-like
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
THBS2 thrombospondin 2
TMEM176B transmembrane protein 176B
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
VGLL4 vestigial-like family member 4