BRD-K72636697_QL-X-138_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K72636697_QL-X-138_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACTA2 actin, alpha 2, smooth muscle, aorta
ADD3 adducin 3 (gamma)
ADGRF5 adhesion G protein-coupled receptor F5
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BHLHE41 basic helix-loop-helix family, member e41
BLNK B-cell linker
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIC5 chloride intracellular channel 5
CLU clusterin
COL14A1 collagen, type XIV, alpha 1
CPE carboxypeptidase E
CRISP3 cysteine-rich secretory protein 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTSA cathepsin A
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
EDN1 endothelin 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ETV1 ets variant 1
FABP4 fatty acid binding protein 4, adipocyte
FAM46A family with sequence similarity 46, member A
GOLGA8A golgin A8 family, member A
GPX3 glutathione peroxidase 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
ITM2A integral membrane protein 2A
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KLF9 Kruppel-like factor 9
NET1 neuroepithelial cell transforming 1
PDGFD platelet derived growth factor D
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PER3 period circadian clock 3
PILRB paired immunoglobin-like type 2 receptor beta
PPAP2A phosphatidic acid phosphatase type 2A
PTCH1 patched 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBKS ribokinase
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SCGB1D2 secretoglobin, family 1D, member 2
SEPP1 selenoprotein P, plasma, 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SPARCL1 SPARC-like 1 (hevin)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CXCL8 chemokine (C-X-C motif) ligand 8
ELOVL6 ELOVL fatty acid elongase 6
FADS1 fatty acid desaturase 1
FAR2 fatty acyl CoA reductase 2
GATA3 GATA binding protein 3
HSPA8 heat shock 70kDa protein 8
IL13RA2 interleukin 13 receptor, alpha 2
KDM3A lysine (K)-specific demethylase 3A
MATN2 matrilin 2
MMP12 matrix metallopeptidase 12
PBX3 pre-B-cell leukemia homeobox 3
PRKCA protein kinase C, alpha
RAD23B RAD23 homolog B (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SFN stratifin
SMC1A structural maintenance of chromosomes 1A
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM158 transmembrane protein 158 (gene/pseudogene)