BRD-K72636697_QL-X-138_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K72636697_QL-X-138_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ARHGAP29 Rho GTPase activating protein 29
BEX1 brain expressed, X-linked 1
C6ORF48 chromosome 6 open reading frame 48
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CD99 CD99 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTGF connective tissue growth factor
DDAH1 dimethylarginine dimethylaminohydrolase 1
DUSP1 dual specificity phosphatase 1
EFNA1 ephrin-A1
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EVL Enah/Vasp-like
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FXR1 fragile X mental retardation, autosomal homolog 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GALC galactosylceramidase
GAS6 growth arrest-specific 6
GLTSCR2 glioma tumor suppressor candidate region gene 2
GPX3 glutathione peroxidase 3
HBP1 HMG-box transcription factor 1
IFITM1 interferon induced transmembrane protein 1
IRS1 insulin receptor substrate 1
KDM3A lysine (K)-specific demethylase 3A
KRT19 keratin 19, type I
LETMD1 LETM1 domain containing 1
LOC283683 uncharacterized LOC283683
LXN latexin
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBR1 neighbor of BRCA1 gene 1
NEFL neurofilament, light polypeptide
NPTX2 neuronal pentraxin II
OLFM1 olfactomedin 1
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLK2 polo-like kinase 2
PRUNE2 prune homolog 2 (Drosophila)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTN pleiotrophin
QPCT glutaminyl-peptide cyclotransferase
RALGDS ral guanine nucleotide dissociation stimulator
SORBS3 sorbin and SH3 domain containing 3
SPATA20 spermatogenesis associated 20
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TSPAN31 tetraspanin 31
TSPAN7 tetraspanin 7
TXNIP thioredoxin interacting protein
VCAN versican
WDR45 WD repeat domain 45
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT7 acyl-CoA thioesterase 7
C20ORF24 chromosome 20 open reading frame 24
CALR calreticulin
CCND3 cyclin D3
CD320 CD320 molecule
CDC25A cell division cycle 25A
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
ENO1 enolase 1, (alpha)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASN fatty acid synthase
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HSPA14 heat shock 70kDa protein 14
KLHL21 kelch-like family member 21
LPL lipoprotein lipase
LTF lactotransferrin
MCM10 minichromosome maintenance complex component 10
MICALL1 MICAL-like 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RAD23B RAD23 homolog B (S. cerevisiae)
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLN sarcolipin
SLPI secretory leukocyte peptidase inhibitor
TFRC transferrin receptor
TSPAN8 tetraspanin 8
TUBA4A tubulin, alpha 4a