BRD-K72636697_QL-X-138_MCF10A_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K72636697_QL-X-138_MCF10A_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
AHNAK AHNAK nucleoprotein
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
C6ORF62 chromosome 6 open reading frame 62
CTGF connective tissue growth factor
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP1 epithelial membrane protein 1
EPHB2 EPH receptor B2
EZR ezrin
GJA1 gap junction protein, alpha 1, 43kDa
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
KLF2 Kruppel-like factor 2
KRT19 keratin 19, type I
MDFIC MyoD family inhibitor domain containing
MDK midkine (neurite growth-promoting factor 2)
METTL7A methyltransferase like 7A
NPR3 natriuretic peptide receptor 3
PEG10 paternally expressed 10
PLAU plasminogen activator, urokinase
RGCC regulator of cell cycle
RHOBTB3 Rho-related BTB domain containing 3
TACSTD2 tumor-associated calcium signal transducer 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TPBG trophoblast glycoprotein
TXNIP thioredoxin interacting protein
WFDC2 WAP four-disulfide core domain 2
ZNF185 zinc finger protein 185 (LIM domain)
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
CA12 carbonic anhydrase XII
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CHGB chromogranin B
CXCL14 chemokine (C-X-C motif) ligand 14
CYTL1 cytokine-like 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DHCR24 24-dehydrocholesterol reductase
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EREG epiregulin
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
FAM134B family with sequence similarity 134, member B
FERMT1 fermitin family member 1
FN1 fibronectin 1
GPX3 glutathione peroxidase 3
H2AFZ H2A histone family, member Z
HSPH1 heat shock 105kDa/110kDa protein 1
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IGKV1-5 immunoglobulin kappa variable 1-5
IL1R2 interleukin 1 receptor, type II
INSM1 insulinoma-associated 1
IVNS1ABP influenza virus NS1A binding protein
JAG1 jagged 1
LAPTM4B lysosomal protein transmembrane 4 beta
MCM6 minichromosome maintenance complex component 6
MKKS McKusick-Kaufman syndrome
MSMO1 methylsterol monooxygenase 1
NELL2 NEL-like 2 (chicken)
NOP56 NOP56 ribonucleoprotein
NSFL1C NSFL1 (p97) cofactor (p47)
NXT1 nuclear transport factor 2-like export factor 1
PANK2 pantothenate kinase 2
PCNA proliferating cell nuclear antigen
PI3 peptidase inhibitor 3, skin-derived
PLCB4 phospholipase C, beta 4
PLIN2 perilipin 2
PRNP prion protein
PTPRA protein tyrosine phosphatase, receptor type, A
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RRBP1 ribosome binding protein 1
SEC23B Sec23 homolog B (S. cerevisiae)
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNRPB2 small nuclear ribonucleoprotein polypeptide B
SNX5 sorting nexin 5
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAB1 stabilin 1
TMEM230 transmembrane protein 230
TMEM45A transmembrane protein 45A
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRAPPC3 trafficking protein particle complex 3
TXNDC9 thioredoxin domain containing 9
TYMS thymidylate synthetase