BRD-K72615639_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K72615639_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AK4 adenylate kinase 4
APOD apolipoprotein D
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA2 carbonic anhydrase II
CCND2 cyclin D2
CCNE2 cyclin E2
CFD complement factor D (adipsin)
CLIC4 chloride intracellular channel 4
CRABP2 cellular retinoic acid binding protein 2
DDIT4 DNA-damage-inducible transcript 4
EGLN3 egl-9 family hypoxia-inducible factor 3
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HIST1H2BG histone cluster 1, H2bg
HSPA13 heat shock protein 70kDa family, member 13
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV3-19 immunoglobulin lambda variable 3-19
KDM3A lysine (K)-specific demethylase 3A
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RAB25 RAB25, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPAG4 sperm associated antigen 4
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TMEM45A transmembrane protein 45A
TPPP3 tubulin polymerization-promoting protein family member 3
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ANXA3 annexin A3
AURKA aurora kinase A
CNN3 calponin 3, acidic
COL3A1 collagen, type III, alpha 1
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CST1 cystatin SN
CX3CR1 chemokine (C-X3-C motif) receptor 1
FZD7 frizzled class receptor 7
HOXA10 homeobox A10
HOXA5 homeobox A5
HSPA1A heat shock 70kDa protein 1A
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LBH limb bud and heart development
LEF1 lymphoid enhancer-binding factor 1
LMNB2 lamin B2
LYPD1 LY6/PLAUR domain containing 1
MVP major vault protein
NAV2 neuron navigator 2
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
NTS neurotensin
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
QKI QKI, KH domain containing, RNA binding
TBC1D4 TBC1 domain family, member 4
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMPRSS11E transmembrane protease, serine 11E
TUBB2B tubulin, beta 2B class IIb