BRD-K72264770_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K72264770_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
F3 coagulation factor III (thromboplastin, tissue factor)
HK2 hexokinase 2
IRS2 insulin receptor substrate 2
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KDM4B lysine (K)-specific demethylase 4B
MET MET proto-oncogene, receptor tyrosine kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
PER1 period circadian clock 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
TCF4 transcription factor 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
CANT1 calcium activated nucleotidase 1
CCL5 chemokine (C-C motif) ligand 5
CD40 CD40 molecule, TNF receptor superfamily member 5
ERBB4 erb-b2 receptor tyrosine kinase 4
HSPA1A heat shock 70kDa protein 1A
LPAR6 lysophosphatidic acid receptor 6
PTGER4 prostaglandin E receptor 4 (subtype EP4)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT1 troponin T type 1 (skeletal, slow)
TUSC3 tumor suppressor candidate 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon