BRD-K72029282_Probucol_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K72029282_Probucol_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ALDOB aldolase B, fructose-bisphosphate
ASPN asporin
AUTS2 autism susceptibility candidate 2
CAPG capping protein (actin filament), gelsolin-like
CPA3 carboxypeptidase A3 (mast cell)
FMO3 flavin containing monooxygenase 3
HOPX HOP homeobox
HOXC6 homeobox C6
MME membrane metallo-endopeptidase
PAWR PRKC, apoptosis, WT1, regulator
PPL periplakin
TFF3 trefoil factor 3 (intestinal)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AHR aryl hydrocarbon receptor
ARHGAP29 Rho GTPase activating protein 29
C1ORF115 chromosome 1 open reading frame 115
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD24 CD24 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLU clusterin
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
FGG fibrinogen gamma chain
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GJA1 gap junction protein, alpha 1, 43kDa
GTPBP8 GTP-binding protein 8 (putative)
HEXIM1 hexamethylene bis-acetamide inducible 1
HSPA1A heat shock 70kDa protein 1A
ITM2A integral membrane protein 2A
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LYPLA1 lysophospholipase I
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MPZL1 myelin protein zero-like 1
MTUS1 microtubule associated tumor suppressor 1
NFIB nuclear factor I/B
OAT ornithine aminotransferase
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRNP prion protein
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
RFK riboflavin kinase
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
STOM stomatin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TOP2A topoisomerase (DNA) II alpha 170kDa
USP1 ubiquitin specific peptidase 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)