BRD-K71935468_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K71935468_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANGPT1 angiopoietin 1
ATF3 activating transcription factor 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAG3 BCL2-associated athanogene 3
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EMP1 epithelial membrane protein 1
FAM107A family with sequence similarity 107, member A
FOSL1 FOS-like antigen 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KRT19 keratin 19, type I
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP1B microtubule-associated protein 1B
MIR22HG MIR22 host gene
MSMO1 methylsterol monooxygenase 1
NUCB2 nucleobindin 2
PIP prolactin-induced protein
RGS10 regulator of G-protein signaling 10
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDF2L1 stromal cell-derived factor 2-like 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SNAI2 snail family zinc finger 2
SPARCL1 SPARC-like 1 (hevin)
THBS1 thrombospondin 1
TRIB3 tribbles pseudokinase 3
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1

decreased expression

Symbol Name
AGRN agrin
GPNMB glycoprotein (transmembrane) nmb
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LGALS3 lectin, galactoside-binding, soluble, 3
PFKM phosphofructokinase, muscle
PLK1 polo-like kinase 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1