BRD-K71879491_tretinoin_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K71879491_tretinoin_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
CASP7 caspase 7, apoptosis-related cysteine peptidase
CP ceruloplasmin (ferroxidase)
DACH1 dachshund family transcription factor 1
EDNRA endothelin receptor type A
GATA2 GATA binding protein 2
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HP haptoglobin
IDO1 indoleamine 2,3-dioxygenase 1
LCN2 lipocalin 2
LRRC17 leucine rich repeat containing 17
MLEC malectin
NMRK1 nicotinamide riboside kinase 1
OLFM4 olfactomedin 4
PLBD1 phospholipase B domain containing 1
PLIN2 perilipin 2
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RGCC regulator of cell cycle
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SOD2 superoxide dismutase 2, mitochondrial
SPINK1 serine peptidase inhibitor, Kazal type 1
TMEM176B transmembrane protein 176B
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AKAP12 A kinase (PRKA) anchor protein 12
C1ORF115 chromosome 1 open reading frame 115
CAV2 caveolin 2
CD200 CD200 molecule
CNN3 calponin 3, acidic
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
HHEX hematopoietically expressed homeobox
METRN meteorin, glial cell differentiation regulator
MYH10 myosin, heavy chain 10, non-muscle
RPS4Y1 ribosomal protein S4, Y-linked 1
SORBS2 sorbin and SH3 domain containing 2
TGFBR3 transforming growth factor, beta receptor III
TPD52L1 tumor protein D52-like 1