BRD-K71303366_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K71303366_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACOT9 acyl-CoA thioesterase 9
ACOX2 acyl-CoA oxidase 2, branched chain
ANXA1 annexin A1
ANXA2P2 annexin A2 pseudogene 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CALR calreticulin
CHN1 chimerin 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
EMP1 epithelial membrane protein 1
FADS1 fatty acid desaturase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGKC immunoglobulin kappa constant
INSIG1 insulin induced gene 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LDLR low density lipoprotein receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MSMO1 methylsterol monooxygenase 1
NUPR1 nuclear protein, transcriptional regulator, 1
ODC1 ornithine decarboxylase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
RNASE4 ribonuclease, RNase A family, 4
RPL38 ribosomal protein L38
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
VIM vimentin

decreased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
CA2 carbonic anhydrase II
CCND2 cyclin D2
CENPN centromere protein N
CPB1 carboxypeptidase B1 (tissue)
DLK1 delta-like 1 homolog (Drosophila)
GATA2 GATA binding protein 2
GRB14 growth factor receptor-bound protein 14
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TFPI2 tissue factor pathway inhibitor 2