BRD-K71303366_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K71303366_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPG capping protein (actin filament), gelsolin-like
CCDC92 coiled-coil domain containing 92
CD14 CD14 molecule
CD24 CD24 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK19 cyclin-dependent kinase 19
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRABP2 cellular retinoic acid binding protein 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FBLN1 fibulin 1
FLRT2 fibronectin leucine rich transmembrane protein 2
GJA1 gap junction protein, alpha 1, 43kDa
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
IDO1 indoleamine 2,3-dioxygenase 1
IFRD1 interferon-related developmental regulator 1
KLK6 kallikrein-related peptidase 6
MTMR11 myotubularin related protein 11
NEFH neurofilament, heavy polypeptide
NT5E 5'-nucleotidase, ecto (CD73)
PADI2 peptidyl arginine deiminase, type II
PI3 peptidase inhibitor 3, skin-derived
PLAU plasminogen activator, urokinase
PTN pleiotrophin
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
SNX7 sorting nexin 7
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SYNGR3 synaptogyrin 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ATF5 activating transcription factor 5
ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC109B coiled-coil domain containing 109B
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
GNAS GNAS complex locus
GNG5 guanine nucleotide binding protein (G protein), gamma 5
HSPB11 heat shock protein family B (small), member 11
KRT13 keratin 13, type I
LRRC41 leucine rich repeat containing 41
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA5 melanoma antigen family A5
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
MAP7 microtubule-associated protein 7
MBOAT7 membrane bound O-acyltransferase domain containing 7
MMP3 matrix metallopeptidase 3
MSLN mesothelin
MYCBP MYC binding protein
PDE10A phosphodiesterase 10A
PTGDS prostaglandin D2 synthase 21kDa (brain)
SPINK1 serine peptidase inhibitor, Kazal type 1
TSPYL5 TSPY-like 5
WBP5 WW domain binding protein 5