BRD-K70914287_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-K70914287_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CCDC92 coiled-coil domain containing 92
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
COMP cartilage oligomeric matrix protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
LDLR low density lipoprotein receptor
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TM4SF1 transmembrane 4 L six family member 1
TSC22D1 TSC22 domain family, member 1
TST thiosulfate sulfurtransferase (rhodanese)
TXNDC9 thioredoxin domain containing 9

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASCL1 achaete-scute family bHLH transcription factor 1
BCHE butyrylcholinesterase
BEX1 brain expressed, X-linked 1
EDNRA endothelin receptor type A
FAM46A family with sequence similarity 46, member A
FSD1 fibronectin type III and SPRY domain containing 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LAPTM4B lysosomal protein transmembrane 4 beta
PDE8B phosphodiesterase 8B
RFTN1 raftlin, lipid raft linker 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)