BRD-K70914287_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K70914287_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AREG amphiregulin
CCNG2 cyclin G2
CD46 CD46 molecule, complement regulatory protein
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CST1 cystatin SN
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
FDPS farnesyl diphosphate synthase
GRN granulin
HMGB3 high mobility group box 3
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IFI27 interferon, alpha-inducible protein 27
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
PDZK1IP1 PDZK1 interacting protein 1
PLK2 polo-like kinase 2
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
TARP TCR gamma alternate reading frame protein
TXNIP thioredoxin interacting protein
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AFP alpha-fetoprotein
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
C3 complement component 3
CHMP4A charged multivesicular body protein 4A
COCH cochlin
COL2A1 collagen, type II, alpha 1
CSRP2 cysteine and glycine-rich protein 2
DLK1 delta-like 1 homolog (Drosophila)
EED embryonic ectoderm development
EIF1AX eukaryotic translation initiation factor 1A, X-linked
GABPB1 GA binding protein transcription factor, beta subunit 1
IFRD2 interferon-related developmental regulator 2
KIF14 kinesin family member 14
MT1F metallothionein 1F
MTDH metadherin
NQO1 NAD(P)H dehydrogenase, quinone 1
POSTN periostin, osteoblast specific factor
PRKCD protein kinase C, delta