BRD-K70792160_Akt inhibitor X_HA1E_6.0_h_24.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K70792160_Akt inhibitor X_HA1E_6.0_h_24.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
CCDC28A coiled-coil domain containing 28A
CCL5 chemokine (C-C motif) ligand 5
ETV1 ets variant 1
FABP4 fatty acid binding protein 4, adipocyte
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLRX glutaredoxin (thioltransferase)
HBP1 HMG-box transcription factor 1
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
LAPTM5 lysosomal protein transmembrane 5
NGRN neugrin, neurite outgrowth associated
NR2F1 nuclear receptor subfamily 2, group F, member 1
NT5DC2 5'-nucleotidase domain containing 2
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PERP PERP, TP53 apoptosis effector
PPAP2B phosphatidic acid phosphatase type 2B
S100A9 S100 calcium binding protein A9
SQSTM1 sequestosome 1
TKT transketolase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BEX1 brain expressed, X-linked 1
CDC25A cell division cycle 25A
CXCL14 chemokine (C-X-C motif) ligand 14
CYR61 cysteine-rich, angiogenic inducer, 61
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DLC1 DLC1 Rho GTPase activating protein
EFNB2 ephrin-B2
EGF epidermal growth factor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCHO1 FCH domain only 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
LAMP5 lysosomal-associated membrane protein family, member 5
MOK MOK protein kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TUFT1 tuftelin 1
ZW10 zw10 kinetochore protein