BRD-K70792160_Akt inhibitor X_A549_6.0_h_24.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

51 genes differentially expressed following the BRD-K70792160_Akt inhibitor X_A549_6.0_h_24.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BZW2 basic leucine zipper and W2 domains 2
C6ORF62 chromosome 6 open reading frame 62
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DENND1B DENN/MADD domain containing 1B
EPS8 epidermal growth factor receptor pathway substrate 8
FZD6 frizzled class receptor 6
GNPDA1 glucosamine-6-phosphate deaminase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
INSIG1 insulin induced gene 1
LRRC15 leucine rich repeat containing 15
MN1 meningioma (disrupted in balanced translocation) 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RAP1GAP RAP1 GTPase activating protein
SCD stearoyl-CoA desaturase (delta-9-desaturase)
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
CCL2 chemokine (C-C motif) ligand 2
CFB complement factor B
CHGB chromogranin B
CHI3L2 chitinase 3-like 2
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
CRABP1 cellular retinoic acid binding protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
FRZB frizzled-related protein
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
LCN2 lipocalin 2
MMP9 matrix metallopeptidase 9
MT1F metallothionein 1F
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OLFM4 olfactomedin 4
PDZK1IP1 PDZK1 interacting protein 1
PEG3 paternally expressed 3
PLAGL1 pleiomorphic adenoma gene-like 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAI2 retinoic acid induced 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SFRP1 secreted frizzled-related protein 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2