BRD-K70642949_GSK-2334470_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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53 genes differentially expressed following the BRD-K70642949_GSK-2334470_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BANK1 B-cell scaffold protein with ankyrin repeats 1
CCND1 cyclin D1
CD44 CD44 molecule (Indian blood group)
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CXADR coxsackie virus and adenovirus receptor
EMP2 epithelial membrane protein 2
EZR ezrin
GULP1 GULP, engulfment adaptor PTB domain containing 1
IFI27 interferon, alpha-inducible protein 27
MLPH melanophilin
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PAWR PRKC, apoptosis, WT1, regulator
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLS1 plastin 1
REG1B regenerating islet-derived 1 beta
RGS13 regulator of G-protein signaling 13
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC38A1 solute carrier family 38, member 1
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3
UBA1 ubiquitin-like modifier activating enzyme 1
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DAPK1 death-associated protein kinase 1
EIF5 eukaryotic translation initiation factor 5
FGFR3 fibroblast growth factor receptor 3
HILPDA hypoxia inducible lipid droplet-associated
HOPX HOP homeobox
HTRA1 HtrA serine peptidase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITM2A integral membrane protein 2A
KANK1 KN motif and ankyrin repeat domains 1
KLK10 kallikrein-related peptidase 10
KLK6 kallikrein-related peptidase 6
MAP7 microtubule-associated protein 7
MYRF myelin regulatory factor
PCNA proliferating cell nuclear antigen
PMM2 phosphomannomutase 2
PNP purine nucleoside phosphorylase
PRKCH protein kinase C, eta
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPW1 selenoprotein W, 1
TM9SF3 transmembrane 9 superfamily member 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3