BRD-K70511574_sunitinib_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K70511574_sunitinib_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BZW2 basic leucine zipper and W2 domains 2
DAAM1 dishevelled associated activator of morphogenesis 1
DLK1 delta-like 1 homolog (Drosophila)
FKBP5 FK506 binding protein 5
GRWD1 glutamate-rich WD repeat containing 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
HSPD1 heat shock 60kDa protein 1 (chaperonin)
LDLR low density lipoprotein receptor
LXN latexin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEA6 melanoma antigen family A6
MCTP1 multiple C2 domains, transmembrane 1
PCM1 pericentriolar material 1
PFKP phosphofructokinase, platelet
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMAD3 SMAD family member 3
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARMCX6 armadillo repeat containing, X-linked 6
ASRGL1 asparaginase like 1
ENO2 enolase 2 (gamma, neuronal)
EXOSC4 exosome component 4
FBLN1 fibulin 1
FRY furry homolog (Drosophila)
HBB hemoglobin, beta
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
MDK midkine (neurite growth-promoting factor 2)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PTGIS prostaglandin I2 (prostacyclin) synthase
RPS5 ribosomal protein S5
SCGB2A1 secretoglobin, family 2A, member 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFTPB surfactant protein B
SULF1 sulfatase 1
TRIM22 tripartite motif containing 22
WDR7 WD repeat domain 7
WFDC2 WAP four-disulfide core domain 2
WNT5A wingless-type MMTV integration site family, member 5A