BRD-K70511574_sunitinib_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K70511574_sunitinib_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL20 chemokine (C-C motif) ligand 20
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
FOSL1 FOS-like antigen 1
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HBEGF heparin-binding EGF-like growth factor
HIST1H1C histone cluster 1, H1c
IPO13 importin 13
PPL periplakin
SESN1 sestrin 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNIP1 TNFAIP3 interacting protein 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CDK1 cyclin-dependent kinase 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
ERBB2 erb-b2 receptor tyrosine kinase 2
GPX2 glutathione peroxidase 2
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
LTBP1 latent transforming growth factor beta binding protein 1
SNAP25 synaptosomal-associated protein, 25kDa
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C