BRD-K70327191_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

37 genes differentially expressed following the BRD-K70327191_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
DGKA diacylglycerol kinase, alpha 80kDa
FOXJ3 forkhead box J3
GADD45A growth arrest and DNA-damage-inducible, alpha
GSTA1 glutathione S-transferase alpha 1
HMOX1 heme oxygenase 1
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KRT13 keratin 13, type I
KRT81 keratin 81, type II
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PLK2 polo-like kinase 2
QPCT glutaminyl-peptide cyclotransferase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SRGN serglycin
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHD7 chromodomain helicase DNA binding protein 7
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GPC3 glypican 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
PEG10 paternally expressed 10
SOBP sine oculis binding protein homolog (Drosophila)
TYRP1 tyrosinase-related protein 1