BRD-K69932463_AZD-8055_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K69932463_AZD-8055_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPH aspartate beta-hydroxylase
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG1 B-cell translocation gene 1, anti-proliferative
CAV1 caveolin 1, caveolae protein, 22kDa
CD9 CD9 molecule
COL15A1 collagen, type XV, alpha 1
CXCL10 chemokine (C-X-C motif) ligand 10
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FAM46A family with sequence similarity 46, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
GLUL glutamate-ammonia ligase
GRB7 growth factor receptor-bound protein 7
KIAA0355 KIAA0355
LDHB lactate dehydrogenase B
MYO6 myosin VI
PLAU plasminogen activator, urokinase
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPS4Y1 ribosomal protein S4, Y-linked 1
SNAP25 synaptosomal-associated protein, 25kDa
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TPD52L1 tumor protein D52-like 1
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
C1ORF116 chromosome 1 open reading frame 116
CCND2 cyclin D2
CDC25A cell division cycle 25A
COCH cochlin
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCN decorin
DEGS1 delta(4)-desaturase, sphingolipid 1
DHCR24 24-dehydrocholesterol reductase
HP haptoglobin
IGKV1-5 immunoglobulin kappa variable 1-5
SEPW1 selenoprotein W, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SPP1 secreted phosphoprotein 1
TGFA transforming growth factor, alpha
TGM2 transglutaminase 2
TLR4 toll-like receptor 4
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM47 transmembrane protein 47
YARS tyrosyl-tRNA synthetase
YBX3 Y box binding protein 3