BRD-K69932463_AZD-8055_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K69932463_AZD-8055_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
CCL5 chemokine (C-C motif) ligand 5
CXCL10 chemokine (C-X-C motif) ligand 10
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFNA1 ephrin-A1
ERLIN2 ER lipid raft associated 2
FBN2 fibrillin 2
GBP1 guanylate binding protein 1, interferon-inducible
GLUL glutamate-ammonia ligase
IFI16 interferon, gamma-inducible protein 16
IRS1 insulin receptor substrate 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PAN2 PAN2 poly(A) specific ribonuclease subunit
PTX3 pentraxin 3, long
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RFTN1 raftlin, lipid raft linker 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPATA20 spermatogenesis associated 20
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
THBD thrombomodulin
TM4SF1 transmembrane 4 L six family member 1
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
ARG2 arginase 2
ASRGL1 asparaginase like 1
CDC6 cell division cycle 6
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
ENO1 enolase 1, (alpha)
FADS1 fatty acid desaturase 1
GINS2 GINS complex subunit 2 (Psf2 homolog)
GPI glucose-6-phosphate isomerase
GPM6B glycoprotein M6B
HOXC6 homeobox C6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LAGE3 L antigen family, member 3
LAPTM4B lysosomal protein transmembrane 4 beta
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTF lactotransferrin
MCM6 minichromosome maintenance complex component 6
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
PGAM1 phosphoglycerate mutase 1 (brain)
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRDX2 peroxiredoxin 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SMC1A structural maintenance of chromosomes 1A
TUBB2A tubulin, beta 2A class IIa