BRD-K69932463_AZD-8055_MCF10A_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

71 genes differentially expressed following the BRD-K69932463_AZD-8055_MCF10A_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP9 A kinase (PRKA) anchor protein 9
AQP1 aquaporin 1 (Colton blood group)
AUTS2 autism susceptibility candidate 2
CCNG2 cyclin G2
CD151 CD151 molecule (Raph blood group)
CD24 CD24 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COMP cartilage oligomeric matrix protein
CTSB cathepsin B
CYTH1 cytohesin 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGFR epidermal growth factor receptor
FBN2 fibrillin 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FN1 fibronectin 1
HIST1H2AC histone cluster 1, H2ac
IGSF3 immunoglobulin superfamily, member 3
JAG1 jagged 1
KIF14 kinesin family member 14
MET MET proto-oncogene, receptor tyrosine kinase
METTL7A methyltransferase like 7A
MT1X metallothionein 1X
MTSS1 metastasis suppressor 1
MYL12B myosin, light chain 12B, regulatory
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLRP2 NLR family, pyrin domain containing 2
NRN1 neuritin 1
PPL periplakin
RPL37A ribosomal protein L37a
RPS4Y1 ribosomal protein S4, Y-linked 1
SIRT3 sirtuin 3
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TRPS1 trichorhinophalangeal syndrome I
TSC22D3 TSC22 domain family, member 3
WEE1 WEE1 G2 checkpoint kinase

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ADI1 acireductone dioxygenase 1
ATF5 activating transcription factor 5
CDC25A cell division cycle 25A
CELF2 CUGBP, Elav-like family member 2
CLGN calmegin
CLIC5 chloride intracellular channel 5
DACH1 dachshund family transcription factor 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
FABP6 fatty acid binding protein 6, ileal
FADS1 fatty acid desaturase 1
FRZB frizzled-related protein
HBB hemoglobin, beta
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA14 heat shock 70kDa protein 14
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MYLK myosin light chain kinase
NREP neuronal regeneration related protein
PEA15 phosphoprotein enriched in astrocytes 15
PLN phospholamban
PPIF peptidylprolyl isomerase F
PRPF4 pre-mRNA processing factor 4
RGS5 regulator of G-protein signaling 5
RPIA ribose 5-phosphate isomerase A
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SRSF7 serine/arginine-rich splicing factor 7
SUB1 SUB1 homolog (S. cerevisiae)
TF transferrin
TFF1 trefoil factor 1
WT1 Wilms tumor 1