BRD-K69932463_AZD-8055_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K69932463_AZD-8055_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
BCL6 B-cell CLL/lymphoma 6
BTG2 BTG family, member 2
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CST3 cystatin C
CTGF connective tissue growth factor
DCN decorin
DUSP6 dual specificity phosphatase 6
ELOVL5 ELOVL fatty acid elongase 5
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FZD7 frizzled class receptor 7
GPER1 G protein-coupled estrogen receptor 1
HES1 hes family bHLH transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
JCHAIN joining chain of multimeric IgA and IgM
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LBH limb bud and heart development
LTF lactotransferrin
MAMLD1 mastermind-like domain containing 1
MYO6 myosin VI
NFIB nuclear factor I/B
PTN pleiotrophin
RGS13 regulator of G-protein signaling 13
SFRP4 secreted frizzled-related protein 4
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SOX4 SRY (sex determining region Y)-box 4
SRPX sushi-repeat containing protein, X-linked
STAP1 signal transducing adaptor family member 1
STK17A serine/threonine kinase 17a
VLDLR very low density lipoprotein receptor
WISP2 WNT1 inducible signaling pathway protein 2

decreased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CALB1 calbindin 1, 28kDa
CALML4 calmodulin-like 4
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CDC25A cell division cycle 25A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT4 DNA-damage-inducible transcript 4
FGFR2 fibroblast growth factor receptor 2
FRZB frizzled-related protein
FXYD2 FXYD domain containing ion transport regulator 2
GSTA1 glutathione S-transferase alpha 1
HILPDA hypoxia inducible lipid droplet-associated
HIST1H1C histone cluster 1, H1c
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MAT2A methionine adenosyltransferase II, alpha
MT1F metallothionein 1F
PDZK1IP1 PDZK1 interacting protein 1
PEX11A peroxisomal biogenesis factor 11 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PRKCB protein kinase C, beta
PRPF4 pre-mRNA processing factor 4
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A8 S100 calcium binding protein A8
STMN2 stathmin 2
SYT1 synaptotagmin I