BRD-K69932463_AZD-8055_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K69932463_AZD-8055_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BIK BCL2-interacting killer (apoptosis-inducing)
BPHL biphenyl hydrolase-like (serine hydrolase)
C10ORF10 chromosome 10 open reading frame 10
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHIC2 cysteine-rich hydrophobic domain 2
CPD carboxypeptidase D
EGR1 early growth response 1
EPCAM epithelial cell adhesion molecule
ERBB3 erb-b2 receptor tyrosine kinase 3
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXN3 forkhead box N3
GABARAPL1 GABA(A) receptor-associated protein like 1
GDF15 growth differentiation factor 15
GNS glucosamine (N-acetyl)-6-sulfatase
GRB7 growth factor receptor-bound protein 7
GSN gelsolin
HBP1 HMG-box transcription factor 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JMJD1C jumonji domain containing 1C
KDM3A lysine (K)-specific demethylase 3A
LAMP1 lysosomal-associated membrane protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCOLN1 mucolipin 1
PEG10 paternally expressed 10
PLCL1 phospholipase C-like 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBPMS RNA binding protein with multiple splicing
RHOB ras homolog family member B
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFRP1 secreted frizzled-related protein 1
SOX4 SRY (sex determining region Y)-box 4
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TFPI2 tissue factor pathway inhibitor 2
TNS3 tensin 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VTCN1 V-set domain containing T cell activation inhibitor 1
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
C5ORF30 chromosome 5 open reading frame 30
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CD24 CD24 molecule
CD320 CD320 molecule
CDC25A cell division cycle 25A
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLCA4 chloride channel accessory 4
CREB1 cAMP responsive element binding protein 1
DDIT4 DNA-damage-inducible transcript 4
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
ECM1 extracellular matrix protein 1
EIF5 eukaryotic translation initiation factor 5
EMP3 epithelial membrane protein 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
GLIPR1 GLI pathogenesis-related 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
MALL mal, T-cell differentiation protein-like
MAT2A methionine adenosyltransferase II, alpha
MCUR1 mitochondrial calcium uniporter regulator 1
MFAP5 microfibrillar associated protein 5
PI3 peptidase inhibitor 3, skin-derived
PMEPA1 prostate transmembrane protein, androgen induced 1
POSTN periostin, osteoblast specific factor
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFN stratifin
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPINK5 serine peptidase inhibitor, Kazal type 5
SPP1 secreted phosphoprotein 1
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon