BRD-K69932463_AZD-8055_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K69932463_AZD-8055_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ADRB2 adrenoceptor beta 2, surface
AIM1 absent in melanoma 1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHGB chromogranin B
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXADR coxsackie virus and adenovirus receptor
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40
DMTF1 cyclin D binding myb-like transcription factor 1
EGR3 early growth response 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLK5 kallikrein-related peptidase 5
KRT14 keratin 14, type I
LGALS1 lectin, galactoside-binding, soluble, 1
NEFH neurofilament, heavy polypeptide
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDLIM5 PDZ and LIM domain 5
PPL periplakin
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SFRP1 secreted frizzled-related protein 1
SNAP25 synaptosomal-associated protein, 25kDa
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STMN2 stathmin 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VAV3 vav 3 guanine nucleotide exchange factor
VSNL1 visinin-like 1
ZBTB38 zinc finger and BTB domain containing 38

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EIF5 eukaryotic translation initiation factor 5
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFR2 fibroblast growth factor receptor 2
GATA2 GATA binding protein 2
HSPA1A heat shock 70kDa protein 1A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITM2C integral membrane protein 2C
LIMCH1 LIM and calponin homology domains 1
LYZ lysozyme
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPIF peptidylprolyl isomerase F
PTPRO protein tyrosine phosphatase, receptor type, O
RBP1 retinol binding protein 1, cellular
S100P S100 calcium binding protein P
SDF2L1 stromal cell-derived factor 2-like 1
SPP1 secreted phosphoprotein 1
TGFA transforming growth factor, alpha