BRD-K69888333_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K69888333_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ADIRF adipogenesis regulatory factor
AKAP12 A kinase (PRKA) anchor protein 12
ALDOC aldolase C, fructose-bisphosphate
C10ORF10 chromosome 10 open reading frame 10
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
CPM carboxypeptidase M
CPT1A carnitine palmitoyltransferase 1A (liver)
CTGF connective tissue growth factor
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPYSL3 dihydropyrimidinase-like 3
DRAM1 DNA-damage regulated autophagy modulator 1
ENG endoglin
F13A1 coagulation factor XIII, A1 polypeptide
FN1 fibronectin 1
FXYD6 FXYD domain containing ion transport regulator 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GBP2 guanylate binding protein 2, interferon-inducible
GLRX glutaredoxin (thioltransferase)
HEPH hephaestin
HOMER3 homer scaffolding protein 3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IL32 interleukin 32
KRT23 keratin 23, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS4 lectin, galactoside-binding, soluble, 4
MAN1A1 mannosidase, alpha, class 1A, member 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MT1X metallothionein 1X
MXRA5 matrix-remodelling associated 5
NBL1 neuroblastoma 1, DAN family BMP antagonist
NDRG1 N-myc downstream regulated 1
NOTCH3 notch 3
PAM peptidylglycine alpha-amidating monooxygenase
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PLIN2 perilipin 2
PPAP2A phosphatidic acid phosphatase type 2A
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RGS16 regulator of G-protein signaling 16
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCPEP1 serine carboxypeptidase 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP4 secreted frizzled-related protein 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC46A3 solute carrier family 46, member 3
SNAI2 snail family zinc finger 2
SOD2 superoxide dismutase 2, mitochondrial
SOX9 SRY (sex determining region Y)-box 9
STEAP1 six transmembrane epithelial antigen of the prostate 1
THBS2 thrombospondin 2
THBS4 thrombospondin 4
TMSB15A thymosin beta 15a
TRIM2 tripartite motif containing 2
TSPAN8 tetraspanin 8
UBE2L6 ubiquitin-conjugating enzyme E2L 6
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
ARMT1 acidic residue methyltransferase 1
ATF5 activating transcription factor 5
BAG1 BCL2-associated athanogene
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CDC25A cell division cycle 25A
CLU clusterin
DBF4 DBF4 zinc finger
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERBB2 erb-b2 receptor tyrosine kinase 2
HMG20B high mobility group 20B
ICAM3 intercellular adhesion molecule 3
IL1RN interleukin 1 receptor antagonist
KDM5D lysine (K)-specific demethylase 5D
LIG1 ligase I, DNA, ATP-dependent
MRPL19 mitochondrial ribosomal protein L19
MYCBP MYC binding protein
PNN pinin, desmosome associated protein
RPS4Y1 ribosomal protein S4, Y-linked 1
SERBP1 SERPINE1 mRNA binding protein 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TACSTD2 tumor-associated calcium signal transducer 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNC tenascin C