BRD-K69516039_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K69516039_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
ANO1 anoctamin 1, calcium activated chloride channel
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
BHLHE41 basic helix-loop-helix family, member e41
CALD1 caldesmon 1
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDA cytidine deaminase
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CREB3L2 cAMP responsive element binding protein 3-like 2
CTGF connective tissue growth factor
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLK1 delta-like 1 homolog (Drosophila)
DOCK9 dedicator of cytokinesis 9
DPP4 dipeptidyl-peptidase 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM134B family with sequence similarity 134, member B
FAM3C family with sequence similarity 3, member C
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GLRX glutaredoxin (thioltransferase)
HBB hemoglobin, beta
HCP5 HLA complex P5 (non-protein coding)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HLA-C major histocompatibility complex, class I, C
HOXB2 homeobox B2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
LEF1 lymphoid enhancer-binding factor 1
LRRN3 leucine rich repeat neuronal 3
MME membrane metallo-endopeptidase
MTSS1 metastasis suppressor 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NEFH neurofilament, heavy polypeptide
NID2 nidogen 2 (osteonidogen)
NT5E 5'-nucleotidase, ecto (CD73)
PLAC8 placenta-specific 8
PPAP2B phosphatidic acid phosphatase type 2B
PRAME preferentially expressed antigen in melanoma
PTN pleiotrophin
RBP4 retinol binding protein 4, plasma
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
RGS10 regulator of G-protein signaling 10
RRBP1 ribosome binding protein 1
SAMD9 sterile alpha motif domain containing 9
SCGB1D2 secretoglobin, family 1D, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP4 secreted frizzled-related protein 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TRIM22 tripartite motif containing 22
TSPAN5 tetraspanin 5
TXNIP thioredoxin interacting protein
VIM vimentin
ZBTB18 zinc finger and BTB domain containing 18
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ATF5 activating transcription factor 5
CALML5 calmodulin-like 5
CCNB1 cyclin B1
CCNF cyclin F
CDC45 cell division cycle 45
CDCA4 cell division cycle associated 4
CDKN3 cyclin-dependent kinase inhibitor 3
CRIP2 cysteine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DCK deoxycytidine kinase
DTNA dystrobrevin, alpha
EIF4B eukaryotic translation initiation factor 4B
EIF5 eukaryotic translation initiation factor 5
GATA3 GATA binding protein 3
GATA6 GATA binding protein 6
LMCD1 LIM and cysteine-rich domains 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
MRPS11 mitochondrial ribosomal protein S11
MYBPC1 myosin binding protein C, slow type
NFIB nuclear factor I/B
NPEPL1 aminopeptidase-like 1
NPY1R neuropeptide Y receptor Y1
PALLD palladin, cytoskeletal associated protein
PFN2 profilin 2
PLK2 polo-like kinase 2
RGS5 regulator of G-protein signaling 5
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
SCAND1 SCAN domain containing 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TOR1A torsin family 1, member A (torsin A)
WDR61 WD repeat domain 61
ZMYM2 zinc finger, MYM-type 2