BRD-K68588778_6942543_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K68588778_6942543_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD36B ankyrin repeat domain 36B
ASNS asparagine synthetase (glutamine-hydrolyzing)
BHLHE41 basic helix-loop-helix family, member e41
BTN3A2 butyrophilin, subfamily 3, member A2
C1QTNF3 C1q and tumor necrosis factor related protein 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP10 dual specificity phosphatase 10
FOLR1 folate receptor 1 (adult)
FOXO3 forkhead box O3
GRB10 growth factor receptor-bound protein 10
IGFBP3 insulin-like growth factor binding protein 3
LOC100272216 uncharacterized LOC100272216
MEIS1 Meis homeobox 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYH10 myosin, heavy chain 10, non-muscle
PDGFD platelet derived growth factor D
PDZK1IP1 PDZK1 interacting protein 1
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
PURA purine-rich element binding protein A
SEPP1 selenoprotein P, plasma, 1
SLC38A1 solute carrier family 38, member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPON1 spondin 1, extracellular matrix protein
TMEM47 transmembrane protein 47
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
C3ORF14 chromosome 3 open reading frame 14
CAV2 caveolin 2
CD200 CD200 molecule
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
ELOVL6 ELOVL fatty acid elongase 6
G0S2 G0/G1 switch 2
GINS2 GINS complex subunit 2 (Psf2 homolog)
GLRX glutaredoxin (thioltransferase)
HIST1H1C histone cluster 1, H1c
KRT19 keratin 19, type I
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
NID1 nidogen 1
NT5E 5'-nucleotidase, ecto (CD73)
NXN nucleoredoxin
RRM2 ribonucleotide reductase M2
S100P S100 calcium binding protein P
SFRP1 secreted frizzled-related protein 1
SHROOM2 shroom family member 2
TSPAN4 tetraspanin 4
UBE2C ubiquitin-conjugating enzyme E2C
WNT5A wingless-type MMTV integration site family, member 5A