BRD-K68407802_KIN001-055_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K68407802_KIN001-055_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLU clusterin
COMT catechol-O-methyltransferase
CST6 cystatin E/M
DSP desmoplakin
EFHD1 EF-hand domain family, member D1
F12 coagulation factor XII (Hageman factor)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
LPAR1 lysophosphatidic acid receptor 1
MAOB monoamine oxidase B
MB myoglobin
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP7 matrix metallopeptidase 7
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NNMT nicotinamide N-methyltransferase
PDZK1 PDZ domain containing 1
PENK proenkephalin
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SOD2 superoxide dismutase 2, mitochondrial
SOX11 SRY (sex determining region Y)-box 11
TBX3 T-box 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIMP3 TIMP metallopeptidase inhibitor 3
TNC tenascin C
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNNC1 troponin C type 1 (slow)
TPD52L1 tumor protein D52-like 1
TTN titin
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
AEBP1 AE binding protein 1
ARL4C ADP-ribosylation factor-like 4C
ASPN asporin
CCND2 cyclin D2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLC Charcot-Leyden crystal galectin
CLEC2B C-type lectin domain family 2, member B
CLTB clathrin, light chain B
CPE carboxypeptidase E
DPYSL3 dihydropyrimidinase-like 3
FLRT2 fibronectin leucine rich transmembrane protein 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HTRA1 HtrA serine peptidase 1
IGFBP5 insulin-like growth factor binding protein 5
LGALS1 lectin, galactoside-binding, soluble, 1
LYZ lysozyme
MAN2A1 mannosidase, alpha, class 2A, member 1
NCAM1 neural cell adhesion molecule 1
NDNF neuron-derived neurotrophic factor
ODC1 ornithine decarboxylase 1
PDGFC platelet derived growth factor C
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLLP plasmolipin
PTCH1 patched 1
RAD51C RAD51 paralog C
RGS10 regulator of G-protein signaling 10
RGS5 regulator of G-protein signaling 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRRM2 serine/arginine repetitive matrix 2