BRD-K68336408_tyrphostin-AG-1478_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

58 genes differentially expressed following the BRD-K68336408_tyrphostin-AG-1478_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AZU1 azurocidin 1
C2CD2L C2CD2-like
CA1 carbonic anhydrase I
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CLCA4 chloride channel accessory 4
ELANE elastase, neutrophil expressed
FAM134B family with sequence similarity 134, member B
FAM69A family with sequence similarity 69, member A
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
LXN latexin
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MYB v-myb avian myeloblastosis viral oncogene homolog
PLAC8 placenta-specific 8
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRTN3 proteinase 3
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100P S100 calcium binding protein P
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TARP TCR gamma alternate reading frame protein
TRAPPC6A trafficking protein particle complex 6A
VCAN versican

decreased expression

Symbol Name
ADCK3 aarF domain containing kinase 3
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
CD47 CD47 molecule
CDC25B cell division cycle 25B
CLU clusterin
CRISP3 cysteine-rich secretory protein 3
CXCL14 chemokine (C-X-C motif) ligand 14
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
GPRC5B G protein-coupled receptor, class C, group 5, member B
GSTM3 glutathione S-transferase mu 3 (brain)
HMGN3 high mobility group nucleosomal binding domain 3
IFI27 interferon, alpha-inducible protein 27
IGHD immunoglobulin heavy constant delta
KRT10 keratin 10, type I
LYPLA1 lysophospholipase I
MALL mal, T-cell differentiation protein-like
NSG1 neuron specific gene family member 1
PLS3 plastin 3
RBM3 RNA binding motif (RNP1, RRM) protein 3
RHOB ras homolog family member B
SPEN spen family transcriptional repressor
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TSPAN8 tetraspanin 8
XIST X inactive specific transcript (non-protein coding)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1