BRD-K68313733_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K68313733_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
COL6A2 collagen, type VI, alpha 2
CXCL6 chemokine (C-X-C motif) ligand 6
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
EIF5A eukaryotic translation initiation factor 5A
FOSL1 FOS-like antigen 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GLUL glutamate-ammonia ligase
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KRAS Kirsten rat sarcoma viral oncogene homolog
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM4 olfactomedin 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOWAHC sosondowah ankyrin repeat domain family member C
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFF3 trefoil factor 3 (intestinal)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNPO1 transportin 1
TUBB2A tubulin, beta 2A class IIa
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
BAMBI BMP and activin membrane-bound inhibitor
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CRISP3 cysteine-rich secretory protein 3
DEPTOR DEP domain containing MTOR-interacting protein
IFI44L interferon-induced protein 44-like
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
LEF1 lymphoid enhancer-binding factor 1
LEPR leptin receptor
LRRC17 leucine rich repeat containing 17
LXN latexin
PLIN1 perilipin 1
SCGB1D2 secretoglobin, family 1D, member 2
SERINC5 serine incorporator 5
SFRP4 secreted frizzled-related protein 4
SLPI secretory leukocyte peptidase inhibitor
SRPX sushi-repeat containing protein, X-linked
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3
XBP1 X-box binding protein 1