BRD-K68313733_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

50 genes differentially expressed following the BRD-K68313733_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANXA1 annexin A1
AQP9 aquaporin 9
C5AR1 complement component 5a receptor 1
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD52 CD52 molecule
CES1 carboxylesterase 1
COLEC12 collectin sub-family member 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
FABP4 fatty acid binding protein 4, adipocyte
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
G6PD glucose-6-phosphate dehydrogenase
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IER5 immediate early response 5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LPL lipoprotein lipase
NCF2 neutrophil cytosolic factor 2
NQO1 NAD(P)H dehydrogenase, quinone 1
PDGFA platelet-derived growth factor alpha polypeptide
PIP prolactin-induced protein
PLBD1 phospholipase B domain containing 1
PLIN2 perilipin 2
RAP1GAP RAP1 GTPase activating protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
CA2 carbonic anhydrase II
CD200 CD200 molecule
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FHL2 four and a half LIM domains 2
GCH1 GTP cyclohydrolase 1
MELK maternal embryonic leucine zipper kinase
PRSS23 protease, serine, 23
TMSB15A thymosin beta 15a